Why the study?
Hypertension is common in autosomal dominant polycystic kidney disease before renal function declines, but the coexistence of hypertension and hypokalemia is rare in these patients.
Case Report (n=1)
No
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease. Hypertension is common and occurs before decline in renal function. However, the coexistence of hypertension and hypokalemia is rare in ADPKD patients. We report on a 32-year-old woman with secondary aldosteronism. Magnetic resonance imaging of the renal arteries revealed multiple cysts of varying sizes in both the kidneys and the liver, compatible with ADPKD. Increased reninangiotensin-aldosterone system activity was secondary to cyst expansion. After initiation of angiotensin II receptor blocker, her blood pressure was controlled without additional requirement of potassium.
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Vutthikraivit et al. (2016) conducted a case report in Autosomal dominant polycystic kidney disease (ADPKD) with secondary aldosteronism, hypertension, and hypokalemia (n=1). Valsartan was evaluated on Control of blood pressure and resolution of hypokalemia.
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