Key result
Altered vascular physiology drives arterial stiffness and polygenic vascular disease by disrupting circulatory homeostasis.
Why the study?
Exploring unknown facts of vascular physiology requires further in vivo small animal, in vitro vascular cell line, in silico bioinformatics, and clinical studies.
Informs haemodynamic monitoring in vascular care; leaves open targeted genetic therapies for arterial stiffness.
A functional aspect of the vascular system is defined as vascular physiology, which covers mostly cardiovascular, cerebrovascular, renovascular and pulmonary vascular systems. Most of the system functions with perfect homeostasis under the coverage of haemodynamics. This haemodynamics maintains a steady relationship between intravascular pressure (P), overall vascular resistance (R) and circulatory flow (F). To explore more unknown facts of vascular physiology further research in experimental physiology with small animals by in vivo, vascular cell line research by in vitro, applications of bioinformatics tools by in silico and clinical studies are needed.
No takes yet. Share an insight, caveat, or question.
Kusal Kanti Das (2022) conducted an editorial in Vascular diseases. Vascular physiology maintains circulatory homeostasis through intravascular pressure, resistance, and flow, with alterations leading to arterial stiffness and polygenic vascular diseases.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: