Fundus cameras deployed in tropical clinics accumulate heat-induced lens haze that degrades image contrast in ways that differ across camera bodies, operators and sessions, yet interpretability audits of diabetic retinopathy graders typically assume a stationary image-formation process. The framework separates a grader's discriminative ranking from its probability calibration and defines a haze-conditional calibration gap as the divergence between calibration curves estimated under clear and hazed acquisition. A before-after-control-impact design is characterised analytically under a declared variance structure with an intraclass correlation of 0.64, between-cluster standard deviation of 6.0 and residual standard deviation of 4.5; power was estimated across 2000 replications per design cell for cluster counts of 8, 16, 24 and 32 and effect sizes of 3, 5 and 8 percentage points. The design requires 52 clusters to detect a 5-percentage-point calibration gap at 80% power. The contribution is a formal statement of when interpretability audits can distinguish haze-induced miscalibration from sampling noise, together with the audit quantities that must be reported for that distinction to be possible.
No takes yet. Share an insight, caveat, or question.
Cherifi et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: