Key result
Histopathology confirms left atrial myxoma in a case where hypervascular imaging mimicked hemangioma.
Why the study?
Primary cardiac tumors are rare, and differentiating atrial myxomas from cardiac hemangiomas is challenging when hypervascular features overlap.
Case Report (n=1)
No
Hypervascularity on multimodal imaging cannot reliably distinguish cardiac myxomas from hemangiomas, underscoring the necessity of histopathological evaluation for definitive diagnosis.
Hypervascular left atrial masses require histopathology for diagnosis; leaves open need for reliable noninvasive discriminators between myxoma and hemangioma.
Background Primary cardiac tumors are rare; atrial myxomas predominate, while hemangiomas represent only 1%–2.8%. Differentiating them is challenging when hypervascular features overlap. Case Summary An 81-year-old woman presented with a large, hypervascular left atrial mass supplied by the circumflex artery. Following uneventful surgical resection, histopathology confirmed a cardiac myxoma despite imaging suggesting a hemangioma. Discussion Hypervascularity cannot reliably distinguish myxomas from hemangiomas. Although multimodal imaging is important for surgical planning, definitive diagnosis relies strictly on histopathological evaluation.
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Barrios et al. (2026) conducted a case report in Highly vascularized left atrial myxoma mimicking a cardiac hemangioma (n=1). Surgical resection and histopathological evaluation was evaluated on Histopathological confirmation of cardiac tumor type. Surgical resection and histopathology in an 81-year-old woman confirmed a left atrial myxoma despite hypervascular imaging mimicking a cardiac hemangioma.
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