Delayed Appearance of Effusive-Constrictive Pericarditis after Radiation for Hodgkin Lymphoma

Letters1 March 1996Delayed Appearance of Effusive-Constrictive Pericarditis after Radiation for Hodgkin LymphomaGregory C. Kane, MD, Richard N. Edie, MD, and John D. Mannion, MDGregory C. Kane, MDJefferson Medical College, Philadelphia, PA 19107Search for more papers by this author, Richard N. Edie, MDJefferson Medical College, Philadelphia, PA 19107Search for more papers by this author, and John D. Mannion, MDJefferson Medical College, Philadelphia, PA 19107Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-5-199603010-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Cardiac complications after mediastinal radiation for Hodgkin lymphoma include coronary artery disease, valvular disease, and acute and chronic pericardial disease [1]. The late appearance of chronic pericardial disease has been reported, but no more than 10 years after radiation [2, 3]. We report two cases of delayed chronic pericardial disease occurring 20 and 23 years, respectively, after treatment of Hodgkin lymphoma.Case 1: A 45-year-old woman with Hodgkin lymphoma who had been treated with mediastinal radiation 23 years previously presented with exertional dyspnea that had lasted 2 months, leg edema, and a transudative pleural effusion. Physical examination ...References1. Stewart JR, Cohn KE, Fajardo LF, Hancock EW, Kaplan HS. Radiation induced heart disease: a study of twenty-five patients. Radiology. 1967; 89:302-10. Google Scholar2. Applefeld MM, Cole JF, Pollock SH, Sulton F, Slawson RG, Singleton RT, et al. The late appearance of chronic pericardial disease in patients treated by radiotherapy for Hodgkin's disease. Ann Intern Med. 1981; 94:338-41. Google Scholar3. Applefeld MM, Slowson RG, Hall-Craigs M, Green DS, Singleton RT, Wiernik PH. Delayed pericardial disease after radiotherapy. Am J Cardiology. 1981; 47:210-3. Google Scholar4. Stewart JR, Fajardo LF. Radiation induced heart disease: an update. Progress in Cardiovascular Disease. 1984; 27:173-94. Google Scholar5. Bookman MA, Longo DL. Complications in patients treated for Hodgkin's disease. Cancer Treat Rev. 1986; 13:77-111. Google Scholar Author, Article, and Disclosure InformationAffiliations: Jefferson Medical College, Philadelphia, PA 19107 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCardio-Oncology: The Role of Echocardiography in Cancer PatientsCardio-oncology: A Focus on CardiotoxicityConstrictive Pericarditis 5 Months after Radiation Therapy in a 62-Year-Old Woman with Esophageal CancerRadiation-Induced Heart DiseaseIsolated Shortness of Breath in a Woman With a History of Hodgkin LymphomaExpert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular ImagingExpert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular ImagingCardiovascular Complications of RadiotherapyDiagnosis of cardiotoxicity: role of conventional and advanced cardiovascular imagingCancer therapy and cardiotoxicity: The need of serial Doppler echocardiographyDelayed effusive pericarditis and recurrent pleural effusion after radiation treatment for Hodgkin's disease responsive to per os doxycyclineLate EffectsConstrictive pericarditis post allogeneic bone marrow transplant for Philadelphia-positive acute lymphoblastic leukaemia 1 March 1996Volume 124, Issue 5Page: 534-535KeywordsBlood pressureDyspneaEdemaHodgkin lymphomaJugular veinMitral insufficiencyPatient advocacyPericardial diseasesPleural effusionRespiration Issue Published: 1 March 1996 CopyrightCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...