Key result
Non-typhoidal Salmonella myopericarditis and pericarditis carry ~31% overall mortality across reviewed cases.
Why the study?
Non-typhoidal salmonella is a rare cause of myopericarditis with varied presenting symptoms, and treatment for myopericarditis has not been well established.
Case Report (n=42)
No
BACKGROUND: Non-typhoidal salmonella (NTS) is a rare, but well-established cause of myopericarditis. Presenting symptoms may be varied, however often revolve around the dual presentation of both myopericarditis and infectious diarrhoea. Given the rarity of NTS related myopericarditis, we conducted a systematic review of the literature, identifying 41 previously reported cases. CASE SUMMARY: infection. After further investigation with echocardiogram and laboratory blood tests, a diagnosis of NTS associated myopericarditis was made, and the patient received antibiotic treatment with an excellent clinical outcome. Overall, myopericarditis is rare in NTS. Although treatment for myopericarditis has not been well established, there are guidelines for the treatment of NTS infection. In our review, we found that the majority of NTS cases has been pericarditis (27/42, 64.3%), with an average age of 48.3 years, and 71.4% being male. The average mortality across all cases was 31%. CONCLUSION: Myopericarditis is a rare, but potentially serious complication of NTS infection, associated with an increased morbidity and mortality.
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Kao et al. (2019) conducted a case report in Non-typhoidal salmonella associated myopericarditis, myocarditis, or pericarditis (n=42). Non-typhoidal Salmonella infection (index case treated with ceftriaxone and azithromycin) was evaluated on Overall mortality across reported cases. Non-typhoidal Salmonella myopericarditis and pericarditis presented predominantly as pericarditis (64.3%) with an overall mortality rate of 31% across 42 reviewed cases.
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