Key result
High-dose glucocorticoids normalize LVEF from ~18% and resolve pericardial effusion in severe SLE myopericarditis.
Why the study?
Symptomatic myocardial involvement is a rare manifestation of systemic lupus erythematosus despite a relatively high prevalence of myocarditis at autopsy.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
Supports steroid use in rare SLE myopericarditis; hypothesis-generating and requires prospective validation before practice change.
Myocardial involvement with clinical symptoms is a rare manifestation of systemic lupus erythematosus (SLE), despite the relatively high prevalence of myocarditis at autopsies of SLE patients. In this review, we report the case of a 19-year-old male SLE patient who initially presented with myopericarditis and was successfully treated with high dose of glucocorticoids.
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Park et al. (2011) conducted a case report in Systemic lupus erythematosus (SLE)-associated myopericarditis (n=1). High-dose glucocorticoids (intravenous methylprednisolone followed by oral prednisolone) was evaluated on Left ventricular ejection fraction (LVEF) normalization and clinical resolution of myopericarditis. High-dose glucocorticoid therapy normalized left ventricular ejection fraction from 18% and resolved pericardial effusion in a 19-year-old male with SLE-associated myopericarditis.
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