Why the study?
Myopericarditis can present with chest pain, ECG ST elevations, and elevated cardiac biomarkers mimicking STEMI, which often leads to activation of ACS protocols and potential administration of thrombolytic therapy.
Case Report (n=1)
No
This case report highlights the diagnostic overlap between acute myopericarditis and STEMI in young adults, illustrating how it can lead to unnecessary thrombolysis and invasive angiography, and reinforces the diagnostic role of cardiac MRI.
Alerts clinicians to myopericarditis as STEMI mimic risking unnecessary thrombolysis in young adults; leaves open prospective validation of MRI-first strategies.
Myopericarditis can present with clinical features similar to ST-elevation myocardial infarction (STEMI), including chest pain, electrocardiographic (ECG) ST elevations, and elevated cardiac biomarkers. This overlap often leads to the activation of acute coronary syndrome protocols and sometimes the administration of thrombolytic therapy. We report a case of a 24-year-old male initially diagnosed and treated as STEMI based on ECG and enzymatic findings. However, he underwent percutaneous coronary intervention (PCI), which revealed normal coronary arteries, and subsequent cardiac MRI ruled out infarction, confirming the diagnosis of acute myopericarditis. This case highlights the importance of keeping a broad differential diagnosis in young adults presenting with STEMI-like features and reinforces the role of advanced imaging in avoiding unnecessary interventions.
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Shoqeir et al. (2025) conducted a case report in Acute myopericarditis mimicking ST-elevation myocardial infarction (n=1). Tenecteplase thrombolysis and rescue percutaneous coronary intervention followed by colchicine, bisoprolol, and lisinopril was evaluated on Symptom resolution and diagnostic confirmation via coronary angiography and cardiac MRI.
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