Key result
Posterior-lead ECG algorithm identifies the culprit artery in inferior STEMI with up to ~93% accuracy.
Why the study?
Multiple ECG algorithms have been proposed to predict the culprit artery in acute inferior STEMI, motivating a comparison of a new algorithm incorporating ST elevation in posterior leads V7-9 against previously published criteria.
Observational (n=260)
May enhance culprit artery prediction in inferior STEMI; leaves open prospective validation before clinical adoption.
In acute inferior ST-segment elevation myocardial infarction (STEMI), multiple electrocardiographic algorithms have been proposed to predict the culprit artery. Our purpose is to review these and compare them to new algorithm using information regarding ST elevation in posterior leads to predict culprit artery in inferior STEMI. 260 consecutive patients with ST-segment elevation in the inferior ECG leads, and coronary arteriography performed within 7 days of the onset of symptoms were retrospectively analysed. The culprit vessel was predicted by the ECG, and findings were correlated with angiography. We then reviewed the algorithms proposed by Fiol et al and Tierala et al, and applied them for predicting the culprit artery, to the population. Finally, we compared the sensitivities and specificities of the respective algorithms for predicting the culprit artery. Sensitivity and specificity of our algorithm to predict RCA as culprit artery were 83% and 93%, respectively, 93% and 83%, respectively for predicting the LCX as the culprit. When we applied the algorithms of Fiol et al and Tierala et al to our study population, they both resulted in slightly lower specificities for RCA prediction and lower sensitivities for LCX prediction as the culprit artery, compared to our algorithm. Routine recording of posterior precordial leads (V7-9) increases the accuracy of predicting infarct related artery in acute inferior wall MI.
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Choudhary et al. (2018) conducted an observational in Acute inferior ST-segment elevation myocardial infarction (STEMI) (n=260). ECG algorithm using ST-segment elevation in posterior leads (V7-9) vs. Previously published ECG algorithms (Fiol et al. and Tierala et al.) and coronary angiography was evaluated on Accuracy (sensitivity and specificity) for predicting the culprit artery (RCA vs LCX). An ECG algorithm using posterior leads V7-9 predicted the culprit artery in inferior STEMI with 83% sensitivity and 93% specificity for RCA, and 93% sensitivity and 83% specificity for LCX.
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