Adrenocortical tumors are infrequent neoplasms, ranging from benign adenomas to aggressive carcinomas. They usually have an unspecific clinical presentation, thus being a challenge in diagnosis and treatment. The following case report discusses the management of a large, non‐functional adrenocortical tumor with histologically aggressive features, underlining the diagnostic workup, the multidisciplinary surgical approach, and the short‐term postoperative outcome after adrenalectomy. We report the case of a 40‐year‐old female patient presenting with dull left flank pain and a large, non‐functional adrenal mass. She underwent open left adrenalectomy. The resected specimen measured 8.4 × 7.6 × 6.5 cm and was histopathologically diagnosed as adrenocortical carcinoma. She was discharged on the 4th post‐operative day and at the 3‐month follow‐up was found to be disease‐free on imaging.
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Khan et al. (2026) studied this question.
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