Orthogonal arrays with variable numbers of symbols are shown to be universally optimal as fractional factorial designs. The orthogonality of completely regular Youden hyperrectangles (F-hyperrectangles) is defined as a generalization of the orthogonality of Latin squares, Latin hypercubes, and F-squares. A set of mutually orthogonal F-hyperrectangles is seen to be a special kind of orthogonal array with variable numbers of symbols. Theorems on the existence of complete sets of mutually orthogonal F-hyperrectangles are established which unify and generalize earlier results on Latin squares, Latin hypercubes, and F-squares.
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Ching‐Shui Cheng (1980) studied this question.
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