Key result
Ethnic group differences were not associated with significant variations in in-hospital mortality (2.8% overall, p=0.816) or postoperative length of stay (p=0.685) after urgent CABG for AMI.
Why the study?
Ethnic heterogeneity influences cardiometabolic risk in coronary artery disease, but whether it translates into different early outcomes after urgent CABG for AMI in universal-access systems was unclear.
Does ethnicity influence in-hospital mortality and postoperative length of stay in patients undergoing urgent CABG for acute myocardial infarction?
Cohort (n=143)
No
Does ethnicity influence in-hospital mortality and postoperative length of stay in patients undergoing urgent CABG for acute myocardial infarction?
Despite presenting at a younger age and with a higher cardiometabolic burden, South-Asian and other ethnic groups experienced similar in-hospital mortality and postoperative length of stay following urgent CABG for AMI in a universal-access healthcare setting.
Answers are grounded in this paper and cite their sources.
No ethnic mortality differences should not yet change practice; leaves open ethnicity's role in larger prospective cohorts.
Background Ethnic heterogeneity influences cardiometabolic risk in coronary artery disease, but whether it translates into different early outcomes after urgent CABG for acute myocardial infarction (AMI) in universal-access systems is unclear. Methods We retrospectively analysed 143 consecutive patients undergoing CABG for AMI (2015–2022) at a tertiary centre: South-Asian (n=86), Middle-Eastern (n=44), African (n=10), and Other-Asian (n=3). Primary outcomes were in-hospital mortality and postoperative length of stay (PLOS; operative-to-discharge days). Categorical variables were compared using chi-square tests. Given the non-normality of PLOS (Shapiro–Wilk p<0.001 in most strata), PLOS was compared using Welch ANOVA. Results South-Asian patients presented younger than pooled non–South-Asian patients (52.8±8.0 vs 59.7±10.7 years; Δ −6.9 years, 95% CI −10.1 to −3.6; p<0.001) and demonstrated higher metabolic burden (HbA1c 7.68±2.2%; LDL 124.5±51.2 mg/dL; LDL p=0.03). Marked sex imbalance was observed across groups (p<0.001). Surgical approach was predominantly on-pump (136/143; 95.1%) without ethnic variation (p=0.794), and AMI phenotype (NSTEMI vs STEMI) was similar across ethnicities (p=0.604). In-hospital mortality was low (4/143; 2.8%) with no observed difference by ethnicity (0/10 African, 2/44 Middle-Eastern, 2/86 South-Asian, 0/3 Other-Asian; χ²=0.939, p=0.816). Mean PLOS was 14.5±5.9 (African), 16.6±19.9 (Middle-Eastern), 13.9±7.3 (South-Asian), and 17.3±5.5 days (Other-Asian), with no difference on Welch ANOVA (F=0.511, p=0.685). Conclusion Despite ethnic variation in age at presentation and cardiometabolic profile, early postoperative outcomes after CABG for AMI were similar in this single-centre cohort under a universal-access system. However, very small minority strata and low event rates limit power and preclude robust adjusted analyses; findings should be considered exploratory and warrant confirmation in larger multicentre studies.
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Houri et al. (2026) conducted a cohort in Acute myocardial infarction undergoing CABG (n=143). Ethnicity (South-Asian) vs. Other ethnic groups (Middle-Eastern, African, Other-Asian) was evaluated on In-hospital mortality and postoperative length of stay (PLOS) (p=0.816). Ethnic group differences were not associated with significant variations in in-hospital mortality (2.8% overall, p=0.816) or postoperative length of stay (p=0.685) after urgent CABG for AMI.
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