We consider a radially symmetric model of a chronic wound featuring oxygen (w), neutrophils (n), bacteria (b), and chemoattractant (c). The dynamics couple three parabolic equations with a degenerate ODE and include a chemotactic drift for n driven by ∇ c. We prove (ⅰ) local well-posedness and positivity of solutions for nonnegative data using maximal regularity and a contraction map, and (ⅱ) local null-controllability with minimally supported controls via an observability inequality obtained from global Carleman estimates. The nonlinear control follows from Kakutani's fixed point theorem applied to the control-to-state map. The result identifies a small set of localized controllers that steer the system to a steady state at a prescribed time.
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Guffey et al. (2026) studied this question.
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