Why the study?
As percutaneous coronary intervention increasingly replaces coronary artery bypass grafting for hemodynamically significant left main coronary artery disease, this review was conducted to systematize the latest data on endovascular treatment, intravascular imaging, and stenting techniques.
This literature review summarizes current evidence on the safety, stenting techniques, stent platforms, and intravascular imaging applications for percutaneous coronary intervention in patients with left main coronary artery disease.
Hemodynamically significant left main coronary artery disease (LMCAD) not only affects the patient’s quality of life but also increases the risk of myocardial infarction and sudden cardiac death. Coronary artery bypass grafting previously considered the gold standard for surgical correction of LMCAD has recently given way to percutaneous coronary intervention. The present review systematizes the latest data on the possibilities of endovascular treatment in LMCAD patients, including the key studies demonstrating the safety of this approach and those substantiating the intraoperative application of intravascular imaging. The advantages of various stenting techniques and stent platforms are outlined. In addition, the review discusses challenges and potential areas for further research, which could improve the longterm outcomes of minimally invasive endovascular approaches in treating LMCAD patients.
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Arablinsky et al. (2026) conducted a review in Hemodynamically significant left main coronary artery disease (LMCAD). Percutaneous coronary intervention (X-ray endovascular treatment) vs. Coronary artery bypass grafting (CABG) was evaluated.
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