Why the study?
Primary hyperaldosteronism has a wide range of clinical manifestations and can follow an atypical clinical course, presenting suddenly with ventricular arrhythmias after a long period of essential hypertension without symptomatic signs of secondary origin.
Case Report (n=1)
No
This case report highlights that primary hyperaldosteronism with persistent hypokalemia can present atypically as polymorphic ventricular tachycardia, requiring preoperative stabilization with amiodarone and aldosterone antagonists prior to adrenal tumor surgery.
This article describes a clinical case of the detection of primary hyperaldosteronism (PA) a 37-years-old female patient has. The patient was urgently hospitalized at the Cardiology department because of stable polymorphic ventricular tachycardis (V-tach) episode. The feature of the disease in her case is a sudden manifestation of PA in the form of ventricular arrhythmias compared with the long period of essential hypertension (EH) without symptomatic origin signs. The detailing of diagnostic steps confirms the importance of potassium level determining for patients with arrhythmia when they are taken to hospitals. Electrolyte analysis is an important aspect of the diagnostic search with a persistent elevated blood pressure and without traditional risk factors EH. In the present case the persistent hypokalemia without anamnestic preconditions for likelihood of electrolyte disturbances has been detected. Primary hyperaldosteronism has a wide range of clinical manifestations described in the medical literature. Present observation confirms the possibility of an atypical clinical course of PA, and it shows objective suitability of searching of adrenal tumors as a reason for letal arrhythmias occurrence. Ventricular rhythm disturbances in the PA are probable option of electrical instability of the myocardium that occurs against the background of grave electrolyte disorders. In this observation medication-assisted treatment with amiodaron, aldosteron antagonists stabilizided the patient`s condition during the preoperative period. This clinical case demonstrates continuity between physicians of various specialties (cardiologist, endocrinologist, surgeon-urologist) during diagnosis and treatment with aldosteronism, as well it considers the peculiarities of cardiologic support for patients with rhythm disturbances, in need surgery of adrenal tumors.
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Sokolov et al. (2026) conducted a case report in Primary hyperaldosteronism with stable polymorphic ventricular tachycardia (n=1). Amiodarone and aldosterone antagonists was evaluated on Preoperative clinical stabilization.
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