Clinical significance of myocardial layer-specific ventricular-arterial coupling index in community populations

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Community populations assessed for ventricular-arterial coupling (n=398). Intervention: Myocardial layer-specific ventricular-arterial coupling index (AVI and AVI/GCS ratios) vs. Conventional arterial elastance (Ea) and demographic/BMI subgroups. Primary outcome: Diagnostic performance across age strata and repeatability of Arterial Velocity Pulse Index (AVI) (95% CI 0.574-0.884, p=<0.001).

Juan Dong; Lingheng Wu; Xinqi Wang; Guiyang Xi; Anni Chen; Lan Yang; Jing Ma; Ning Wang; Lin Jin; Zhaojun Li

doi:10.21037/qims-2026-1167

October 14, 2026Quantitative Imaging in Medicine and SurgeryOpen Access

Clinical significance of myocardial layer-specific ventricular-arterial coupling index in community populations

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Study Design

Type

Cross-Sectional (n=398)

PICO

P

Population

398 community-dwelling adults (mean age 49.6 years, 58.0% female, including 147 overweight/obese individuals) evaluated by echocardiography for layer-specific ventricular-arterial coupling.

E

Exposure / Comparator

Myocardial layer-specific ventricular-arterial coupling index (AVI and AVI/GCS ratios) vs Conventional arterial elastance (Ea) and demographic/BMI subgroups

O

Primary Outcome

Diagnostic performance across age strata and repeatability of Arterial Velocity Pulse Index (AVI) (0.574-0.884), p=<0.001

Main Result

p-value: p=<0.001

Limitations

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Abstract

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Discussion

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Cite This Study

Dong et al. (2026) conducted a cross-sectional in Community populations assessed for ventricular-arterial coupling (n=398). Myocardial layer-specific ventricular-arterial coupling index (AVI and AVI/GCS ratios) vs. Conventional arterial elastance (Ea) and demographic/BMI subgroups was evaluated on Diagnostic performance across age strata and repeatability of Arterial Velocity Pulse Index (AVI) (95% CI 0.574-0.884, p=<0.001).

synapsesocial.com/papers/6ae28f41cbadf70daf6c446e https://doi.org/10.21037/qims-2026-1167

View Full Paper

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Clinical significance of myocardial layer-specific ventricular-arterial coupling index in community populations

Study Design

PICO

Main Result

Limitations

Abstract

Discussion

Cite This Study

Clinical significance of myocardial layer-specific ventricular-arterial coupling index in community populations

Study Design

PICO

Main Result

Limitations

Abstract

Discussion

Cite This Study

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