The role of melatonin as a regulator of testicular function has been studied. The results of preclinical studies devoted to the study of the effect of melatonin on male fertility under the influence of various damaging factors are shown. Taking into account the results of preclinical studies, it can be concluded that melatonin is highly effective as an antioxidant in diseases of the male reproductive system, however, large-scale clinical studies are required to include this drug in the treatment regimens for male infertility.
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Neymark et al. (2026) studied this question.
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