Acute acalculous cholecystitis (AAC) is not confined to the critically ill and may behave like calculous disease. A 65‐year‐old hypertensive man with localized, stone‐free cholecystitis deteriorated on hospital Day 4 with peritonism, acidosis, and acute kidney injury. Emergency open cholecystectomy confirmed gangrene; deterioration warrants urgent source control.
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Yassin et al. (2026) studied this question.
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