Infantile hemangioma: modern perspectives on pathogenesis and treatment

Infantile hemangioma (IH) is a significant and common interdisciplinary issue in the pediatric population. The etiology of this condition is not fully understood. Several hypotheses exist regarding the origin of IH: the placental hypothesis, genetic mutations, and the influence of external factors. Treatment approaches for IH are diverse and include systemic pharmacotherapy, local treatment, and surgical intervention. Each of these methods has both advantages and limitations, making it impossible to use any single approach as a universal solution for all patients. The beta-blocker propranolol is currently recognized as the first-line medication. The authors of the lecture presented a literature review of modern approaches to selecting treatment for IH, as well as predictors of propranolol efficacy and its possible mechanism of action.