Do Loop Diuretics Cause Atrial Fibrillation in CKD?

Dr. Bertram PittCardiology

“In conclusion, the study by Ravi et al. associates the use of loop diuretics in CKD with an increase in the risk of hospitalizations for AF. Although confounded by indication, their findings should refocus our attention on the potential risks of loop diuretics in CKD or HF and stimulate further studies on strategies for prevention.”

“A definitive answer to the question of whether loop diuretics really do cause AF in CKD would require a prospective randomized trial that is unlikely to be attempted. There are some recommendations that can be considered to mitigate the potential risks of AF associated with loop diuretic use in patients with CKD or HF.”