ST-Segment Elevation Acute Myocardial Infarction in Argentina: 11 Years of the ARGEN-IAM-ST Registry

Objective: To identify clinical aspects, delays, treatment regimens, and outcomes, as well as potential barriers that need to be addressed in the care of STEMI. Methods: Since December 2014, a national registry has been in place that includes patients with STEMI with a duration of less than 36 hours. Results: As of December 2025, 8,073 patients had been included, with a mean age of 61 years; 79% were male. The infarct location was anterior in 50% of cases. Fifty percent of patients were admitted after being referred from another institution, but only 27% received fibrinolytics prior to referral. The overall reperfusion rate was 93% (10% with fibrinolytics and 80% with primary angioplasty), with treatment times that remain inadequate. Delays in treatment were reported in >60% of cases, particularly during the patient’s initial consultation and transport to the facility; among reperfused patients, the rate was 8%, and 15% among non-reperfused patients. Heart failure at admission was observed in 23% of patients and was one of the most significant predictors of mortality in the multivariate analysis. Discussion: These data provide a snapshot of the current state of acute myocardial infarction (AMI) in Argentina and its evolution over the past 11 years.