Key result
Fatty liver severity correlates moderately with worsening HbA1c, triglycerides, and HDL-C in T2DM.
Why the study?
Fatty liver disease is commonly associated with T2DM, dyslipidaemia, and poor glycaemic control, motivating evaluation of how ultrasonographic fatty liver grading correlates with lipid profile and glycaemic parameters in patients with T2DM.
Cross-Sectional (n=120)
Increasing ultrasonographic severity of fatty liver is significantly associated with worsening glycaemic control (higher HbA1c) and atherogenic dyslipidaemia (higher triglycerides and lower HDL-C) in patients with type 2 diabetes mellitus.
Answers are grounded in this paper and cite their sources.
Supports integrated cardiometabolic evaluation in T2DM; extends cross-sectional correlations but leaves open prospective validation and clinical utility.
Background: Fatty liver disease is commonly associated with type 2 diabetes mellitus (T2DM), dyslipidaemia, and poor glycaemic control. This study aimed to evaluate the correlation of ultrasonographic fatty liver grading with lipid profile and glycaemic parameters in patients with T2DM. Materials and Methods: This hospital-based, cross-sectional study included 120 patients with T2DM. Lipid profile, fasting blood glucose (FBG), postprandial blood glucose (PPBG), and HbA1c were assessed. Fatty liver was graded ultrasonographically, and associations were evaluated using appropriate statistical tests. Results: In the dataset, the mean age was 53.8 ± 10.4 years, and 56.7% were male. Fatty liver was present in 83.3% of patients. HbA1c increased from 6.8 ± 0.7% in Grade 0 to 9.6 ± 1.2% in Grade III, while triglycerides increased from 132.6 ± 28.4 to 242.6 ± 48.5 mg/dL. HDL-C decreased from 48.6 ± 7.2 to 35.4 ± 5.8 mg/dL. correlations were positive for HbA1c (ρ = 0.65) and triglycerides (ρ = 0.62) and negative for HDL-C (ρ = −0.51). Conclusion: Increasing fatty liver severity may be associated with worsening glycaemic control and dyslipidaemia in patients with T2DM.
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Dr. Pooja Kataria1, Dr. Ada Najafi2, Dr. Adnan Naim3 (2026) conducted a cross-sectional in Type 2 diabetes mellitus (n=120). Ultrasonographic fatty liver grading (Grade I-III) vs. Grade 0 fatty liver was evaluated on Correlation of ultrasonographic fatty liver grading with lipid profile (triglycerides, HDL-C) and glycaemic parameters (HbA1c, FBG, PPBG) (ρ = 0.65 (HbA1c), ρ = 0.62 (triglycerides), ρ = −0.51 (HDL-C)). Ultrasonographic fatty liver grading correlated positively with HbA1c (ρ = 0.65) and triglycerides (ρ = 0.62), and negatively with HDL-C (ρ = −0.51) in T2DM patients.
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