Currently, there are few animal models that reflect the physiological complexity of cerebral small vessel disease. Ruan et al. 1 1. Ruan, J. ∙ Nasrollahi, A. ∙ Martin, C. ... Loss of laminin-γ1 in pericytes impairs microvascular function and cognition Cell Rep. 2026; 45 , 117904 Full Text Full Text (PDF) Scopus (1) Google Scholar presented a pericyte-specific knockout of laminin-γ1 that exhibited several key disease-typical characteristic features at 11 months of age.
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Małgorzata Burek (2026) studied this question.
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