Background: Chronic fatigue syndrome (CFS) is a complex and disabling condition characterized by persistent fatigue, cognitive difficulties, impaired functioning, and reduced quality of life. Cognitive Behavioural Therapy (CBT) and Relaxation Therapy (RT) are non-pharmacological approaches that may support symptom management. This study compared the effectiveness of CBT and RT among teaching professionals with CFS. Methods: A prospective, randomized, comparative interventional study was conducted among 100 teaching professionals diagnosed with CFS. Participants were equally allocated to CBT (n=50) and RT (n=50) groups. Fatigue, psychological distress, functioning, work and social adjustment, and quality of life were assessed using the Fatigue Severity Scale (FSS), Multidimensional Fatigue Inventory (MFI), Short Form-36 (SF-36), Depression Anxiety Stress Scale (DASS), Work and Social Adjustment Scale (WSAS), and WHOQOL. Structured group sessions were conducted for 8 weeks. Pre- and post-intervention outcomes were compared using appropriate statistical tests, with p<0.05 considered significant. Results: Both groups showed significant improvements in fatigue, psychological distress, physical functioning, work and social adjustment, and quality of life (p<0.001). Post-intervention FSS scores were lower in the CBT group than the RT group (3.67±0.52 vs. 4.70±0.51). SF-36 physical functioning (68.84±7.01 vs. 60.78±7.16) and WHOQOL scores (69.76±5.46 vs. 60.56±5.96) were also higher with CBT (p<0.001). Conclusion: Both CBT and RT improved psychological well-being, functioning, and quality of life. CBT may be a useful structured supportive intervention for symptom management in appropriately selected teaching professionals with CFS.
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Gurung et al. (2026) studied this question.
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