Study on the Levels of Gingival Crevicular Fluid Cytokines and Periodontal Status in Patients with Anterior Teeth Fan-shaped Displacement Treated with Orthodontic-periodontal Splint Therapy

Objective: This study focuses on the combined application of orthodontic treatment and periodontal splinting, aiming to deeply explore the specific effects of this therapy on the levels of gingival crevicular fluid cytokines and periodontal health status in patients with anterior tooth fan-shaped displacement. Methods: A total of 62 patients with anterior tooth fan-shaped displacement who received combined orthodontic and periodontal splinting treatment between January 2022 and December 2023 were included in the study. They were divided into two groups based on different treatments. The control group (31 cases) received periodontal splinting treatment, while the observation group (31 cases) received combined orthodontic and periodontal splinting treatment. The levels of gingival crevicular fluid cytokines [tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6)] and plaque index (PLI) scores were compared between the two groups. Results: After treatment, the IL-6 and TNF-α levels in the observation group were lower than those in the control group, and the PLI score was also lower than that in the control group (P < 0.05). Conclusion: Combined orthodontic and periodontal splinting treatment for patients with anterior tooth fan-shaped displacement can reduce the levels of gingival crevicular fluid cytokines and improve periodontal status.