Characterization and Utilization of Latex of Plumeria alba for Various Bioactive Studies and Nanoparticle Production for Drug Delivery

ntroduction: The use of plant latex provides an environment friendly alternative for the synthesis of nanocarriers compared to conventional physical and chemical methods. Methods: In this study, latex from Plumeria alba was subjected to chloroform extraction to isolate lipid components. The extract was characterized using UV-Vis Spec-troscopy (UV- Vis), Fourier Transform Infrared Spectroscopy (FTIR) and Gas Chromatography–Mass Spectrometry (GC-MS). The Antibacterial and antioxidant activities of the extracts were evaluated. Drug loaded nanocarriers were then prepared by a microemulsion approach and analyzed using UV-Vis, FTIR and Scanning Electron Microscopy (SEM). Their drug-release performance was subsequently assessed. Results: The chloroform based extract exhibited both antibacterial and antioxidant activities. The synthesized nanocarriers had particle sizes ranging from approxi-mately 450 nm to 920 nm. Among these, the drug-loaded nanocarriers demonstrated notable antibacterial activity, while the formulation on based on chloroform extract showing the highest drug release efficiency in ethanol. Con-clusion: Plumeria alba- derived nanocarriers exhibit promising potential for drug delivery applications due to their biodegradable nature and inherent antioxidant and antibacterial properties, indicating their suitability for future therapeutic use.