Key result
Carotid artery stenting lowers 1-year mean systolic BP by ~8 mmHg.
Why the study?
The short and long-term effects of the carotid artery stenting (CAS) procedure on blood pressure as assessed by ambulatory BP monitoring required evaluation.
Does carotid artery stenting reduce short-term (24-hour) and long-term (1-year) arterial blood pressure measured via ambulatory blood pressure monitoring in patients undergoing the procedure for primary or secondary protection?
Cohort (n=123)
Does carotid artery stenting reduce short-term (24-hour) and long-term (1-year) arterial blood pressure measured via ambulatory blood pressure monitoring in patients undergoing the procedure for primary or secondary protection?
Answers are grounded in this paper and cite their sources.
Carotid artery stenting is associated with significant reductions in both systolic and diastolic ambulatory blood pressure at 24 hours that persist at 1-year follow-up.
BACKGROUND: The aim of this study was to assess the short and long-term effects of carotid artery stenting (CAS) procedure on blood pressure (BP) through ambulatory BP monitoring. METHODS: One hundred fifty three patients who underwent CAS for primary or secondary protection from December 2010 to September 2013 were enrolled to our study. The BP levels of total of 123 patients were monitored for 1 year. Thereafter, the pre-procedure levels of BP were compared with BP levels at the 24-hour and the first year intervals after the procedure. RESULTS: Systolic and diastolic BP levels at the 24-hour and the first year intervals after CAS were significantly lower than the pre-procedure BP levels. The mean 24-hour systolic BP was 113 ± 13 mmHg and diastolic BP was 63 ± 8 mmHg, both of which were significantly lower (p < 0.001 and p < 0.001 respectively), while the pre-procedure mean systolic BP was 133 ± 10 mmHg and the mean diastolic BP was 75 ± 9 mmHg. Moreover, the mean first-year systolic BP was 125 ± 10 mmHg with a decline of 8 ± 8 mmHg and mean diastolic BP was 71 ± 8 mmHg with a decline of 4 ± 7 mmHg, both of which were again significantly lower compared to the pre-procedure levels (p < 0.001 and p < 0.001 respectively). CONCLUSIONS: The results of our study suggested that systolic and diastolic BP levels diminished after CAS. Additionally, BP reduction continued even 1 year after the CAS.
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Köklü et al. (2016) conducted a cohort in Carotid artery disease requiring carotid artery stenting (n=123). Carotid artery stenting (CAS) vs. Pre-procedure baseline blood pressure levels was evaluated on Systolic and diastolic blood pressure levels measured through ambulatory blood pressure monitoring at 24 hours and 1 year (MD -8 mmHg (1-year systolic BP), p=<0.001). Carotid artery stenting significantly reduced mean systolic BP from 133±10 mmHg pre-procedure to 113±13 mmHg at 24h and 125±10 mmHg at 1 year (p<0.001).
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