Analysis of antibiotic resistance of uropathogens in the aspect of empirical therapy

Urinary tract infections are one of the most common categories of bacterial infections in urological practice, with an annual incidence of approximately 150 million cases worldwide. The aim of this study is to optimize the choice of empirical initial therapy in urological practice. Analyzed the results of bacteriological examination of urine samples from patients treated in the urology department in 2018, 2019, and 2020. An assessment of the local susceptibility of uropathogens to antibacterial drugs revealed that the greatest number of microorganisms, according to an individual analysis of digital data, are sensitive to drugs such as gentamicin (an aminoglycoside), clindamycin (a lincosamide), and a penicillin. The conducted antibiotic susceptibility assessment revealed certain trends that must be considered when developing treatment strategies, as well as taking into account regional patterns of antibiotic resistance. The data obtained demonstrate the need for continuous updating of information on microbial susceptibility, as only up-to-date information will minimize errors in the selection of initial therapy.