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chronic rhinosinusitis | endoscopic sinus surgery | patient-reported outcomes | psychological dysfunction | quality of life | SNOT-22 Key Points• ESS produces durable, meaningful benefit in SNOT-22 psychological dysfunction through 5 years.• Lower baseline burden and absence of polyps predict failure to achieve psychological benefit.• Psychiatric comorbidity and medications do not attenuate the psychological benefit from surgery.
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Zhou et al. (2026) studied this question.
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