Negatively Impacting Factors Against Effective Hepatitis B Vaccination

Introduction : Infection by the Hepatitis B virus is one of the greatest global public health issues. One study revealed that the world is facing about 3.61% of the overall HBV infection burden, with significant variation across countries. This study explores the negatively influencing factors that are hampering the effective Hepatitis-B vaccination. Methods: A review of the published studies that were written on the factors that hamper successful hepatitis B vaccination was conducted using the Google Scholar search engine. A total of 26 journal articles on negatively influencing factors of hepatitis B vaccination were studied, and the most relevant items during the last 10 years were identified and analyzed. Results: Overall, 18 barriers have been identified that hinder the effective uptake of hepatitis B vaccines. Those are lack of appropriate awareness and knowledge about Hepatitis B viral vaccination was identified as by far the highest factor and was 69% (18), simultaneiously, not having adequate education among parents is mentioned in more than 41% (11) of studies, followed by superstition and false perception or belief regarding vaccination as well as cultural barriers are also mentioned by 36% (9) of studies. On the other hand, the price of the vaccine and the unavailability of the vaccine are mentioned in 27% (7) of the reviewed articles. The fourth most mentioned barrier was lack of awareness among the health providers, along with inadequate knowledge of HBV among healthcare professionals, which was mentioned by 15% (4) of the reviewed studies. Issues differed from region to region. Conclusion: An appropriately planned and well-organized hepatitis B vaccination policy throughout the nation should be emphasized and prioritized to have adequate vaccine coverage after identifying the negatively influencing factors, and controlling those factors to eradicate the hepatitis B virus from the era. Medicine Today 2026, Vol.38 (2): 324-328