Clinical approach and surgical outcomes of nasolabial cysts with coexisting nasal anatomical variations: A single-center study

Aims: Nasolabial cysts (NLCs) are rare, benign, non-odontogenic lesions of the nasolabial region.The coexistence of NLCs with common nasal anatomical variations has been insufficiently explored in the literature.This study aims to characterize the demographic, clinical, and radiological features of surgically treated NLCs and to document their coexistence with nasal anatomical variations.Methods: This retrospective descriptive case series included patients with histopathologically confirmed NLCs who underwent surgical treatment at a single center between January 2022 and January 2025.Exclusion criteria were irregular followup, refusal of surgery, or absence of histopathological confirmation.Demographic data, clinical symptoms, and findings from computed tomography (CT) and magnetic resonance imaging were assessed, with a focus on the prevalence of coexisting nasal anatomical variations and their relationship to cyst size and bone remodeling.Results: A total of 11 patients were included, with a mean age of 52.55±11.17years; all patients were female.The predominant presenting symptoms were facial swelling (81.8%) and pain secondary to infection (45.5%).Coexisting nasal anatomical variations were identified in 90.9% of patients, most commonly concha bullosa (63.6%), maxillary sinus hypoplasia (36.4%), and septal deviation (27.3%).CT revealed bone remodeling, characterized by smooth pressure-related scalloping of the cortex, in 72.7% of cases; no frank cortical erosion was observed in any patient.The mean anteroposterior diameter was 23.11±4.04mm in cysts with bone remodeling and 18.00±1.73mm in cysts without bone remodeling (exact p=0.009).All patients underwent surgical excision (10 transoral sublabial, 1 endoscopic transnasal), with no recurrence detected during the available follow-up period (mean 13.9 months).Conclusions: NLCs in this series frequently coexisted with nasal anatomical variations.Surgical excision was associated with favorable outcomes and absence of recurrence.