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For a binomial count with n trials and success probability p, the signed log-likelihood ratio at x is the square root of twice the log-likelihood ratio of $x/n$ against p, with the sign of $x/n-p$. Zubkov and Serov proved that, for $0<j<n-1$, the binomial distribution function at j lies between the standard Gaussian distribution function at the signed log-likelihood ratios of j and $j+1$. If the distribution function of the Gamma law with shape k and scale θ at x equals the probability of a negative binomial count with these parameters below an integer m, Harremoës proved that the Gamma signed log-likelihood ratio at x lies between the negative binomial ones at $m-1$ and m, and conjectured that $m-1$ can be raised to $m-1/2$. We prove this conjecture for all k,θ>0. The ratio of the derivatives of the two distribution functions in q=1/(1+θ) is not monotone at $m-1/2$, unlike at $m-1$, and we show that it starts below one and first falls and then rises. Our theorem bounds the binomial distribution function at j by the standard Gaussian distribution function at the signed log-likelihood ratios of $j+1/2$ and $j+1$, with $n+1/2$ in place of n, through a tail identity and a known Gaussian bound for the Gamma law. For $0<j<n-1$, each bound is strictly tighter than the corresponding Zubkov--Serov bound. On a numerical grid, the three-term expressions of Alfers and Dinges, which are bounds only under an unproved convexity condition, are tighter in the ranges for which they recommend them.
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Sungwoo Kang (2026) studied this question.
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