Hypertrophic cardiomyopathy in workers who work in harmful working conditions: aspects of professional aptitude testing

Hypertrophic cardiomyopathy (HCM) is a myocardial disease associated with the risk of sudden cardiac death (SCD). The scientists examined the criteria for diagnosis and anatomical and morphological types, phenocopies of HCM, algorithms for examination and risk stratification of SCD, necessary when addressing issues of professional suitability based on clinical recommendations and regulations (Order of the Ministry of Health of the Russian Federation No. 29n). The clinical observation of a patient with HCM who was sent for a mandatory periodic medical examination is presented. The analysis showed that, according to Order No. 29n, the diagnosis of HCM in itself does not serve as a medical contraindication to work. A restriction of admission occurs if an employee has complications of the disease (life-threatening cardiac arrhythmias, chronic heart failure of functional class III–IV). At the same time, with an asymptomatic, non-obstructive variant of HCM, it is important to assess the risk of SCD according to special risk scales. Access to work with harmful working conditions is possible with a low risk of SCD. Thus, an individual assessment of professional aptitude, based on a comprehensive analysis of the patient's condition, SCD risk stratification data and compliance with industry standards, makes it possible to ensure occupational safety without unreasonable restrictions.Contributions:Gorokhova S.G. — concept and design of the study, data processing, writing;Alpaev D.V. — data collection and processing, writing;Korchagin I.A. — data collection and processing;Strizhakov L.A. — design and editing;Atkov O.Yu. — concept and editing.Funding. The study had no funding.Conflict of interest. The authors declare no conflict of interest.Received: 10.09.2025 / Accepted: 06.10.2025 / Published: 30.10.2025