Prenatal Vitamin C supplementation mediates the association between prenatal distress and infant negative affect: A prospective cohort study.

= .001). Adjusting for covariates, structural equation modeling showed that prenatal vitamin C supplementation, but not dietary vitamin C intake, mediated the association between maternal prenatal distress and infant NA (indirect β = .02, bootstrapped 95% conifidence interval [0.01, 0.05]). As such, lower vitamin C intake during pregnancy may influence fetal neurodevelopment via altering the intrauterine environment. These findings point to prenatal vitamin C supplementation's potential as a modifiable and scalable intervention to promote healthy early socioemotional development. (PsycInfo Database Record (c) 2026 APA, all rights reserved).