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This report describes the first cytogenetically confirmed case of complete trisomy 13 associated with a highly mobile mandibular neonatal tooth and a contralateral eruption cyst associated with an unerupted tooth, managed by bedside surgery in the neonatal intensive care unit. A late-preterm newborn with trisomy 13, unilateral complete cleft lip and palate, and congenital heart disease presented with a highly mobile mandibular neonatal tooth and a contralateral eruption cyst associated with an unerupted tooth. Following multidisciplinary evaluation, both teeth were extracted at the bedside under local anesthesia and cardiorespiratory monitoring, without complications. This case expands the oral phenotypic spectrum of trisomy 13 and underscores the importance of early recognition, individualized management, and Hospital Dentistry in preventing airway-related complications in medically complex newborns.
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Franco et al. (2026) studied this question.
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