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Introduction Suicide is a global health priority, particularly among young people. This systematic review aimed to synthesize current evidence on whether social media data can be used to identify suicide-related risk through psychologically informed machine learning models. Methods PubMed, Web of Science, Scopus, ScienceDirect, and IEEE Xplore were searched for articles published between 2024 and 2026, updating previous searches conducted in July 2021, December 2022, and July 2024. Eligible studies used social media data to detect suicidal thoughts and behaviors (STBs) or suicide risk and incorporated psychologically significant variables or representations into the prediction process. Risk of bias and applicability were assessed using the Prediction model Risk of Bias ASsessment Tool for Artificial Intelligence (PROBAST+AI). Results A total of 18 studies were included. Models incorporated psycholinguistic and affective features, multiple psychological constructs, and, more recently, temporal, relational, and multimodal information. Commonly represented constructs included depression, anxiety, hopelessness, loneliness, perceived burdensomeness, and emotional states. Reported performance varied considerably across studies, with some models achieving area under the curve (AUC) values above 0.90; however, 13 of the 18 studies were judged to have a high overall risk of bias and five an unclear risk, with concerns concentrated particularly in the analysis domain. Discussion Psychologically informed machine learning models show potential for identifying STBs and suicide-related risk from social media data. However, substantial methodological heterogeneity, limited external validation, inconsistent definitions of suicidality, and applicability concerns limit the interpretation and generalizability of current findings. Future research should prioritize externally validated and calibrated models that clearly distinguish between different suicide-related outcomes when assessing individual suicide risk. Systematic review registration https://www.crd.york.ac.uk/PROSPERO/ , identifier CRD42020218349
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García-Martínez et al. (2026) studied this question.
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