Key result
Multimodality imaging identifies a massive ~73-mm right coronary artery aneurysm alongside severe ischemic cardiomyopathy.
Why the study?
Coronary artery aneurysms are uncommon, giant forms are extremely rare, and their nonspecific presentation may mimic other thoracic pathologies.
Case Report (n=1)
Highlights the need to consider systemic aneurysmal predisposition and utilize combined coronary angiography and cross-sectional imaging when evaluating atypical thoracic masses in patients with a history of abdominal aortic aneurysm.
Answers are grounded in this paper and cite their sources.
May prompt coronary imaging in aortic aneurysm patients with mediastinal masses or heart failure; leaves open need for prospective screening studies in systemic arteriopathy.
Background: Coronary artery aneurysms (CAAs) are uncommon, giant forms are extremely rare and the presentation is nonspecific and may mimic other thoracic pathologies. Case Illustration: A 60-year-old male presented with progressive dyspnea, orthopnea, and peripheral edema, five years after open repair of a large fusiform abdominal aortic aneurysm. Echocardiography showed severe left ventricular dysfunction (LVEF 25%) with a mass at the junction of the right atrium and right ventricle, interpreted as a right atrial pseudoaneurysm. CT, however, described an isolated mediastinal mass. Coronary angiography showed a single giant saccular right coronary artery aneurysm (73.1 × 66.9 mm) with trapped contrast and chronic total occlusion of the left main and anterior descending arteries. CT reconstruction indicated the latter occlusion to be a second thrombus-laden coronary aneurysm, to be further evaluated. His previous aortic aneurysm suggested a common predisposition to aneurysms not appreciated during years of disrupted follow-up. He was treated with guideline-directed heart failure, antithrombotic, statin and metabolic therapy. Staged repair was deferred until stabilization. Conclusions: This case demonstrates how a pre-existing diagnosed abdominal aortic aneurysm may mask the recognition of a second coronary aneurysm and perhaps a third in the left coronary system. It emphasizes the importance of considering systemic aneurysmal predisposition in atypical thoracic masses in patients with a history of aortic aneurysm and the role of angiography with cross-sectional imaging in diagnosis.
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Dewi et al. (2026) conducted a case report in Giant right coronary artery aneurysm and severe left ventricular dysfunction (n=1). Guideline-directed heart failure, antithrombotic, statin, and metabolic therapy (with deferred staged repair) was evaluated. Coronary angiography and CT identified a 73.1 x 66.9 mm giant right coronary artery aneurysm and left coronary occlusion in a patient with LVEF 25% and prior abdominal aortic aneurysm repair.
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