Key result
Aortic valve replacement with root reduction plasty achieves ~5 mm root reduction in endocarditis.
Why the study?
Although Streptococcus anginosus is part of the normal human microbiota, its involvement in infective endocarditis is uncommon.
Case Report (n=1)
No
This case report highlights the pathogenic potential of Streptococcus anginosus in bicuspid aortic valve infective endocarditis complicated by paravalvular abscess, demonstrating successful management with early surgical intervention using a mechanical valve, root-conserving reduction plasty, and targeted antimicrobial therapy.
Answers are grounded in this paper and cite their sources.
May support root-conserving surgery in select bicuspid valve endocarditis; leaves open need for prospective validation.
We present a case of infective endocarditis (IE) caused by Streptococcus anginosus in a 39-year-old man with a previously diagnosed bicuspid aortic valve (BAV).Although S. anginosus is part of the normal human microbiota, its involvement in IE is uncommon.The patient presented with a six-week history of nonspecific constitutional symptoms; imaging revealed renal and splenic infarcts, and transoesophageal echocardiography demonstrated aortic valve vegetations with a paravalvular abscess.Blood cultures and molecular testing identified S. anginosus as the causative organism.He underwent aortic valve replacement with a mechanical prosthesis and aortic root reduction plasty; intraoperative findings confirmed a ruptured abscess within the left ventricular outflow tract (LVOT).The postoperative course was uneventful, and he completed a six-week course of targeted antimicrobial therapy.This case underscores the importance of prompt diagnosis and early surgical intervention in patients with BAV who develop IE, particularly when complicated by suppurative lesions, and highlights the pathogenic potential of S. anginosus.It also shows that a root-conserving technique was a feasible option in this patient with a mildly dilated aortic root, although its role compared with root replacement cannot be established from a single case.
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Klavdianou et al. (2026) conducted a case report in Streptococcus anginosus infective endocarditis complicated by paravalvular aortic abscess in a bicuspid aortic valve (n=1). Aortic valve replacement with a 25 mm mechanical prosthesis, aortic root reduction plasty, surgical repair of ruptured LVOT abscess, and targeted antimicrobial therapy (ceftriaxone, gentamicin, and daptomycin) was evaluated on Aortic root diameter reduction and clinical recovery. Aortic valve replacement with root reduction plasty and 6 weeks of antibiotics reduced aortic root diameter from 44 mm to 39 mm and resolved Streptococcus anginosus endocarditis in a 39-year-old man.
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