Key result
Subxiphoid point-of-care echocardiography rapidly detects fatal intraoperative right heart thrombus-in-transit during hip hemiarthroplasty.
Why the study?
Intraoperative massive pulmonary embolism is a rare, catastrophic complication of hip fracture surgery that is easily mistaken for the effects of neuraxial anaesthesia or bone cement implantation syndrome.
Case Report (n=1)
No
In delayed hip fracture surgery under spinal anaesthesia, sudden bradycardia may be the first sign of a massive pulmonary embolism, and bedside echocardiography is critical for diagnosing a right heart thrombus-in-transit even when a preoperative echocardiogram was normal.
Answers are grounded in this paper and cite their sources.
May prompt POCUS consideration in refractory perioperative arrest; hypothesis-generating from single fatal case report.
Intraoperative massive pulmonary embolism is a rare but catastrophic complication of hip fracture surgery that is easily mistaken for the effects of neuraxial anaesthesia or for bone cement implantation syndrome. We report an 86-year-old man with dementia, severe frailty (Clinical Frailty Scale 7) and a body mass index of 19 kg/m2, admitted four days after a fall with a displaced (Garden IV) left femoral neck fracture. Preoperative transthoracic echocardiography was normal; no venous Doppler ultrasound was performed, and enoxaparin prophylaxis was started on admission. Cemented hemiarthroplasty was performed under unilateral hypobaric spinal anaesthesia (bupivacaine 5 mg, fentanyl 25 µg) with low-dose noradrenaline, and the 90-minute procedure was haemodynamically stable. During skin closure, the patient developed extreme bradycardia (35 beats/min) with loss of consciousness, followed by cardiac arrest. After return of spontaneous circulation, subxiphoid point-of-care echocardiography showed a large mobile right atrial thrombus prolapsing into a dilated right ventricle, with paradoxical septal motion. Thrombolysis was withheld because of the immediate postoperative context, and embolectomy was discussed with cardiovascular surgeons. A second arrest (pulseless ventricular tachycardia) was reversed by defibrillation, but a third arrest was refractory, and the patient died after 30 minutes of resuscitation. A normal preoperative echocardiogram does not exclude venous thrombosis after delayed presentation; under spinal anaesthesia, sudden bradycardia may be the first sign of massive embolism, and bedside echocardiography is decisive for the diagnosis.
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En-nasery et al. (2026) conducted a case report in Intraoperative massive pulmonary embolism with right heart thrombus-in-transit during hip hemiarthroplasty for neglected femoral neck fracture (n=1). Cemented hip hemiarthroplasty under unilateral hypobaric spinal anaesthesia with subxiphoid point-of-care echocardiography diagnosis was evaluated on Intraoperative cardiac arrest and death due to massive pulmonary embolism with right heart thrombus-in-transit. Subxiphoid point-of-care echocardiography diagnosed a right heart thrombus-in-transit after bradycardia (35 bpm) and arrest at the end of a 90-minute hip hemiarthroplasty, resulting in death.
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