Key result
Vitamin D may regulate cardiovascular function and blood pressure through vascular, cardiac, and renal receptors.
Why the study?
Hypertension is a significant global contributor to cardiovascular disease and mortality, and vitamin D may play a role in regulating cardiovascular function via receptors in vascular, heart, and kidney tissue.
This review explores the mechanistic, epidemiological, and clinical trial evidence regarding the potential role of vitamin D in regulating cardiovascular function and hypertension.
Answers are grounded in this paper and cite their sources.
Supports mechanistic plausibility; leaves open clinical efficacy questions and should not change practice.
Vitamin D, generally associated with bone health, may also potentially play a role in regulating cardiovascular function, as vitamin D receptors are ubiquitously expressed in the vascular, heart and kidney tissue. Hypertension is a significant contributor to cardiovascular diseases and mortality across the globe.
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Verma et al. (2026) studied this question. Vitamin D may play a role in regulating cardiovascular function and hypertension through receptors expressed in vascular, heart, and kidney tissues.
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