Key result
Computational baffle design maintains DORV pathways below the 10-mmHg threshold across all patients.
Why the study?
Intraventricular baffle geometry for complex biventricular repair is typically shaped intraoperatively, and existing preoperative virtual modeling tools remain predominantly manual with limited watertight models for quantitative hemodynamic assessment.
Does a semi-automated computational framework generate surgically feasible, simulation-ready intraventricular baffle geometries with acceptable hemodynamic pressure differences (<10 mmHg) in pediatric patients with double outlet right ventricle undergoing biventricular repair?
Observational (n=4)
No
Does a semi-automated computational framework generate surgically feasible, simulation-ready intraventricular baffle geometries with acceptable hemodynamic pressure differences (<10 mmHg) in pediatric patients with double outlet right ventricle undergoing biventricular repair?
This study demonstrates a semi-automated computational framework that translates surgeon-defined boundaries into simulation-ready 3D intraventricular baffle models with favorable CFD-derived pressure gradients (<6 mmHg) for preoperative planning in double outlet right ventricle repair.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for semi-automated baffle planning in DORV; larger prospective studies needed before clinical adoption.
Patient-specific computational modeling has emerged as a powerful tool for surgical planning in complex congenital heart disease. One promising application is complex biventricular repair, which often requires construction of a custom intraventricular baffle to establish a physiologic left ventricle-to-aorta outflow pathway. In current practice, baffle geometry is designed and shaped intraoperatively. While existing preoperative modeling tools increasingly support visualization and virtual baffle design, the design process remains predominantly manual, and watertight models for quantitative hemodynamic assessment remain limited. We present a semi-automated computational framework for the design and assessment of patient-specific intraventricular baffles. The method constructs an explicit ventricular septal defect (VSD)-to-aorta flow pathway that preserves native right ventricular myocardial and VSD geometry while reshaping the baffle region to satisfy patient-specific, section-wise area constraints. We retrospectively applied this framework to four patients with double outlet right ventricle (DORV) who had previously undergone biventricular repair. Each generated pathway was evaluated with pulsatile computational fluid dynamics (CFD), producing peak-flow pressure differences of 1.58-5.94 mmHg under the prescribed flow conditions. All modeled pressure differences remained below the 10-mmHg planning benchmark across mesh resolutions and under elevated flow. The current implementation preserves the native VSD and does not model VSD enlargement or conal resection; however, it provides a computational framework through which these interventions could be evaluated in silico. By translating a surgeon-defined baffle boundary into a physiologically constrained, simulation-ready model, this approach enables quantitative preoperative design and CFD-based evaluation of candidate baffle geometries, advancing patient-specific computational planning for biventricular flow restoration in heterogeneous anatomies.
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Martinez et al. (2026) conducted an observational in Double outlet right ventricle (DORV) undergoing biventricular repair (n=4). Semi-automated computational generation and pulsatile CFD evaluation of patient-specific intraventricular surgical baffles vs. Postoperative transthoracic echocardiography and a 10-mmHg clinical planning benchmark was evaluated on Face-averaged peak-flow pressure difference across the reconstructed VSD-to-aorta pathway. Semi-automated computational baffle design generated simulation-ready pathways with peak-flow pressure differences of 1.58-5.94 mmHg, remaining below the 10-mmHg benchmark in all 4 DORV patients.
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