Key result
Delayed PCD-CT angiography resolves carotid web pseudolesions, achieving ~87% relative luminal attenuation.
Why the study?
Carotid web is diagnosed almost entirely from a shelf-like filling defect on CTA, but the posterolateral carotid bulb is also a site of flow separation where blood of differing contrast density mixes. This case report investigated whether a bilateral web-like appearance at this site arose from image reconstruction or acquisition.
Does a delayed, slower ultra-high-resolution photon-counting-detector CT angiogram differentiate flow-related mixing pseudolesions from true bilateral carotid webs in a patient with transient ischemic attack?
Case Report (n=1)
Does a delayed, slower ultra-high-resolution photon-counting-detector CT angiogram differentiate flow-related mixing pseudolesions from true bilateral carotid webs in a patient with transient ischemic attack?
Answers are grounded in this paper and cite their sources.
Flow-related contrast mixing in the carotid bulb can mimic a bilateral carotid web on both energy-integrating and photon-counting CT angiography, which can be resolved with a slower repeat acquisition and a few seconds more delay to prevent unnecessary revascularization.
Purpose Carotid web is diagnosed almost entirely from a shelf-like filling defect at CT angiography (CTA), yet the posterolateral carotid bulb at which webs arise is also a site of flow separation in which blood of differing contrast density mixes. We describe a bilateral web-like appearance at this site and determine whether it arose from reconstruction or acquisition. Methods A 75-year-old woman with a right-hemispheric transient ischemic attack had three carotid CTA examinations: a dual-energy energy-integrating-detector CT (EID-CT) angiogram five months before presentation, a stroke-protocol photon-counting-detector CT (PCD-CT) angiogram at presentation, and a dedicated ultra-high-resolution PCD-CT angiogram three days later. Each photon-counting acquisition was additionally reconstructed with other section thicknesses, kernels or energies, and attenuation across the appearance was measured. Results A bilateral shelf-like filling defect closely simulating a carotid web was present on the EID-CT and presenting PCD-CTF angiograms but absent on the ultra-high-resolution study. The tested reconstructions neither abolished the appearance nor elicited it. The ultra-high-resolution study was acquired 16.6 s after the end of injection at less than half the table speed, versus 10.3 s on the presenting study. Attenuation at the corresponding position measured 62%, 54% and 87% of luminal attenuation, respectively. No carotid intervention was undertaken. Conclusion An acquisition-dependent bilateral carotid bulb pseudolesion can mimic a carotid web on both EID-CT and PCD-CT angiography and is most consistent with flow-related mixing of blood of differing contrast density. A slower repeat acquisition of the carotid bulb with a few seconds more delay may prevent unnecessary revascularization.
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Ben-David et al. (2026) conducted a case report in Suspected bilateral carotid web following right-hemispheric transient ischemic attack (n=1). Dedicated ultra-high-resolution photon-counting-detector CT (PCD-CT) angiography acquired 16.6 s after end of injection at reduced table speed vs. Dual-energy energy-integrating-detector CT (EID-CT) and stroke-protocol photon-counting-detector CT (PCD-CT) acquired 10.3 s after injection was evaluated on Presence of bilateral shelf-like filling defect and relative luminal attenuation across the carotid bulb appearance. Ultra-high-resolution PCD-CT acquired 16.6 s post-injection resolved a pseudolesion mimicking a bilateral carotid web (87% vs 54% luminal attenuation at 10.3 s).
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