Key result
Prolonged VV-ECMO supports successful decannulation and survival in pediatric ALL with severe PARDS.
Why the study?
Pediatric acute respiratory distress syndrome (PARDS) is an important cause of morbidity and mortality in pediatric intensive care units, prompting this report of prolonged VV-ECMO in a child with severe PARDS and acute lymphoblastic leukemia (ALL).
Does prolonged venovenous ECMO enable survival to decannulation and hospital discharge in a child with acute lymphoblastic leukemia and severe refractory PARDS?
Case Report (n=1)
No
Does prolonged venovenous ECMO enable survival to decannulation and hospital discharge in a child with acute lymphoblastic leukemia and severe refractory PARDS?
Prolonged VV-ECMO (34 days) may serve as a feasible rescue strategy for severe, potentially reversible PARDS in carefully selected pediatric patients with ALL and a favorable oncological prognosis.
Answers are grounded in this paper and cite their sources.
Suggests prolonged VV-ECMO feasible in select pediatric ALL-PARDS; leaves open generalizability and requires prospective studies.
Pediatric acute respiratory distress syndrome (PARDS) is an important cause of morbidity and mortality in pediatric intensive care units. We report successful prolonged venovenous extracorporeal membrane oxygenation (VV-ECMO) support in a child with severe PARDS and acute lymphoblastic leukemia (ALL). A 5-year-old boy with low-risk B-cell ALL developed severe refractory PARDS during induction therapy. VV-ECMO was initiated for profound hypoxemia and continued for 34 days, after which he was successfully decannulated. He was discharged after 235 days of hospitalization. This case suggests that prolonged VV-ECMO may be a feasible rescue strategy in carefully selected children with ALL when respiratory failure is potentially reversible and the oncological prognosis is favorable.
No takes yet. Share an insight, caveat, or question.
Özen et al. (2026) conducted a case report in Severe refractory pediatric acute respiratory distress syndrome (PARDS) and low-risk B-cell acute lymphoblastic leukemia (ALL) (n=1). Prolonged venovenous extracorporeal membrane oxygenation (VV-ECMO) was evaluated on Successful decannulation and survival to hospital discharge. Prolonged VV-ECMO for 34 days resulted in successful decannulation and discharge after 235 days in a 5-year-old boy with ALL and severe PARDS.
Synapse has enriched 10 related papers. Consider them for comparative context: