Key result
Phase 4 AV block after TAVR causes recurrent ventricular standstill despite initial conduction recovery.
Case Report (n=1)
Early apparent recovery of 1:1 atrioventricular conduction within 12 hours after TAVR may not predict durable conduction in the presence of latent phase 4 atrioventricular block, necessitating prolonged monitoring around temporary pacemaker removal.
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Alerts clinicians to extended monitoring for late AV block post-TAVR; extends evidence that implantation unmasks latent conduction disease.
Transcatheter aortic valve replacement (TAVR) carries up to a 15% risk of complete heart block (CHB) within 30 days, but the mechanisms driving recurrent heart block after the apparent initial conduction system recovery post-TAVR remain incompletely understood. Phase 4 atrioventricular block, a pause-dependent phenomenon occurring when supraventricular or ventricular impulses encounter diseased His-Purkinje fibers during diastolic depolarization, may contribute to post-TAVR conduction disturbances. We present an instructive case of a 71-year-old woman with severe aortic valve stenosis who developed CHB in the setting of phase 4 atrioventricular block following TAVR. Despite recovering sinus rhythm with 1:1 atrioventricular conduction within 12 hours post-procedure, she experienced recurrent ventricular standstill upon temporary pacemaker removal, ultimately requiring permanent pacemaker implantation. This case illustrates the multiple mechanisms and temporal patterns of post-TAVR conduction system disorders, the potential unreliability of early apparent conduction recovery as a predictor of durable atrioventricular conduction, and the necessity for careful and more prolonged patient monitoring before and after temporary pacemaker removal.
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Reddy et al. (2026) conducted a case report in Severe aortic valve stenosis and post-TAVR phase 4 atrioventricular block (n=1). Transcatheter aortic valve replacement (TAVR) and permanent pacemaker implantation was evaluated on Complete heart block, recurrent ventricular standstill, and permanent pacemaker implantation. Transcatheter aortic valve replacement in a 71-year-old woman led to phase 4 AV block and recurrent ventricular standstill despite 1:1 conduction recovery at 12 hours, requiring permanent pacing.
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