Key result
Exercise triggers the liver to release clusterin into the bloodstream, improving cardiac remodeling and myocyte proliferation following myocardial infarction.
Why the study?
Does exercise improve cardiac remodeling and myocyte proliferation post-myocardial infarction via hepatic clusterin release?
Does exercise improve cardiac remodeling and myocyte proliferation post-myocardial infarction via hepatic clusterin release?
Answers are grounded in this paper and cite their sources.
Exercise-induced release of clusterin from the liver may improve cardiac remodeling and myocyte proliferation following myocardial infarction.
Wang and colleagues 1 demonstrate that exercise triggers the liver to release clusterin into the bloodstream, improving cardiac remodeling and myocyte proliferation post-myocardial infarction. Their findings add another mechanistic facet to the complexity and controversial role of clusterin in cardiac injury.
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Finck et al. (2026) studied this question. Exercise triggers the liver to release clusterin into the bloodstream, improving cardiac remodeling and myocyte proliferation following myocardial infarction.
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