Evaluation of High-Fluence 1470 nm Non-Ablative Fractional Diode Laser in Cutaneous Scar Remodeling: A Two-Case Clinical Report and Descriptive Quantitative Analysis

Cutaneous scars resulting from trauma or surgical intervention often cause functional impairment, cosmetic discomfort, and psychological distress. Non-ablative fractional lasers (NAFL) stimulate dermal neocollagenesis while maintaining epidermal integrity. To describe clinical outcomes, tolerability, and changes in measured scar dimensions following high-energy 1470 nm non-ablative fractional diode laser treatment in two patients. Two female patients with Fitzpatrick skin types II and III presented with facial scars following traumatic injury (Patient 1) and surgical lip-lift intervention (Patient 2) were enrolled in this clinical study. Treatments were administered using a 1470 nm diode laser (LaserMe) at high energy fluences (38–40 mJ/point) with tight spot spacing (1.0 mm). Dimensional metrics (length and width) and clinical scores via the Subject Global Aesthetic Improvement Scale (SGAIS) were monitored. At the last reported dimensional assessment (Day 93 in the pooled scar-level table), the glabellar scar decreased in length from 3.2 to 2.0 cm (37.5%) and in width from 6.5 to 3.0 mm (53.8%). The right subnasal scar decreased by 15.4% in length and 25.0% in width; the left subnasal scar decreased by 37.5% in length and 50.0% in width. Both patients were rated much improved (SGAIS = 1). No persistent pigmentary adverse events were reported within the documented observation period. In these two cases, 1470 nm non-ablative fractional diode laser treatment demonstrated potential for scar remodeling with acceptable short-term tolerability. Larger controlled studies with longer follow-up are needed.