Coexisting Clear Cell Renal Cell Carcinoma and Renal Angiomyolipoma: An 8‐Year Imaging Follow‐Up Case Report

We report a case of coexisting clear cell renal cell carcinoma (ccRCC) and renal angiomyolipoma (AML) with an eight-year imaging follow-up. A 28-year-old woman was initially diagnosed with a 16-mm fat-containing renal lesion in 2017. Serial ultrasonography demonstrated gradual enlargement. In 2023, CT revealed a new 12-mm non-fatty solid nodule that was not detected on ultrasound. By 2025, the solid component had enlarged to 32 mm and showed marked contrast enhancement. Following partial nephrectomy, pathology confirmed coexisting ccRCC (WHO/ISUP grade 2) and AML. No local recurrence was observed at the one-year postoperative follow-up. This case highlights the importance of recognizing new or enlarging solid components in presumed AMLs and emphasizes the value of multimodal imaging in evaluating evolving fat-containing renal lesions.