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Orthodontic relapse is a common complication in orthodontic treatment, referring to the tendency of teeth to shift back to their original position after orthodontic forces are discontinued. This condition is influenced by multiple biological and mechanical factors, including incomplete bone remodeling, imbalance in neuromuscular adaptation, continued craniofacial growth, and unfavorable oral habits that affect long term stability. Although retainers are routinely used to maintain tooth alignment, their effectiveness depends greatly on patient compliance, which often limits optimal outcomes. For this reason, alternative approaches involving natural agents with bioactive compounds have gained increasing attention as supportive therapies. This literature review analyzed eight scientific articles published between 2019 and 2025 from reputable databases to evaluate several natural materials, including Stichopus hermanii, Vitis vinifera, Anadara granosa, Hibiscus sabdariffa Linn, Olea europaea, and Triticum aestivum. The findings indicate that some agents stimulate osteogenesis and periodontal regeneration, while others inhibit osteoclastogenesis and provide antioxidant effects. Together, these complementary mechanisms suggest promising potential in preventing orthodontic relapse.
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Aulia et al. (2026) studied this question.
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