A Firefly‐Inspired Biomimetic Multispectral Cascade Framework for Transient Thermal Mitigation and Tissue Protection in High‐Power Laser Surgeries

High‐power laser systems remain indispensable in modern clinical surgeries owing to their superior cutting precision and structural blood occlusion capabilities. However, collateral thermal damage manifesting as rapid localized carbonization, tissue scarring, and secondary peripheral cell death remains a major complication due to unmitigated macroscale heat accumulation. Traditional mechanical methods, such as air‐flow cooling or liquid cryogen sprays, suffer from structural latency and block critical intraoperative visualization fields. To resolve this photothermal bottleneck, this study introduces a novel theoretical framework: an active, firefly‐inspired biomimetic coaxial optical buffering shielding engine designed for transient millisecond‐scale spatial–temporal thermal mitigation. By engineering a hardware‐native cascaded energy transport model, localized high‐energy thermal photons generated during target tissue cutting are captured by a peripheral spectral absorption layer. This system dynamically shifts the localized photon energy across a multispectral cascade grid, mimicking the cascading energy transfer topologies observed in bioluminescent mechanisms to dissipate structural thermal waste as nondestructive, minimized‐thermal luminescent output. Multiphysics numerical co‐simulations demonstrate that this biomimetic cascading network restricts peripheral tissue temperatures to safe physiological boundaries below 43°C via a closed‐loop control law, achieving a 35.4% reduction in peak peripheral heat diffusion and decreasing collateral cellular necrosis depth by up to 48.2% without compromising core ablation efficiency, thereby establishing a translation‐ready milestone framework for precision photomedicine.