Malignant Tumor of the Thymus Gland, Myasthenia Gravis Developing After Removal

Case Reports1 April 1951MALIGNANT TUMOR OF THE THYMUS GLAND, MYASTHENIA GRAVIS DEVELOPING AFTER REMOVALJOHN B. FERSHTAND, M.D., F.A.C.P., ROBERT R. SHAW, M.D.JOHN B. FERSHTAND, M.D., F.A.C.P.Search for more papers by this author, ROBERT R. SHAW, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-34-4-1025 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInterest in tumors of the thymus gland has been stimulated by their association with myasthenia gravis. Blalock,1, 2Clagett3, 4and others have reported on the sometimes apparently beneficial results of thymectomy in this disease. This case is unique in that symptoms of myasthenia gravis developed for the first time after subtotal removal of a malignant thymic tumor. We have been unable to find any reports of a similar occurrence in the literature. The duration of the known existence of this tumor, its great size, length of life after the appearance of symptoms, and the magnitude of involvement of the...Bibliography1. Blalock A: Tumors of the thymic region in myasthenia gravis, Am. J. Surg. 54: 149, 1941. CrossrefGoogle Scholar2. BlalockHarveyFordLibenthal AAMFRJL: The treatment of myasthenia gravis by removal of the thymus gland, J. A. M. A. 111: 1529, 1941. CrossrefGoogle Scholar3. ClagettEaton OTLM: Thymic tumors in myasthenia gravis, S. Clin. North America 23: 1076, 1943. Google Scholar4. ClagettEaton OTLM: Surgical treatment of myasthenia gravis, J. Thoracic Surg. 16: 62, 1947. CrossrefGoogle Scholar5. Symmers D: Malignant tumors and tumor-like growths of the thymic region, Ann. Surg. 95: 544, 1932. CrossrefMedlineGoogle Scholar6. WilsonPritchard FNJE: Malignant thymomas, Canad. M. A. J. 53: 444, 1945. MedlineGoogle Scholar7. Harrell GT: Hodgkin's disease with invasion of the pericardium and gall bladder, review of the literature and report of case with autopsy, Arch. Path. 28: 58, 1939. Google Scholar8. Ritvo M: Hodgkin's disease; report of case with unusual longevity and invasion of heart and pericardium, New England J. Med. 223: 891, 1940. CrossrefGoogle Scholar9. McCoy JJ: Hodgkin's disease involving the pericardium, U. S. Naval M. Bull. 48: 272, 1948. MedlineGoogle Scholar10. Good CA: Roentgenologic findings in myasthenia gravis associated with thymic tumors, Am. J. Roentgenol. 57: 305, 1947. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 19, 1949.From the Harris Hospital, Fort Worth, Texas, and the Baylor Hospital, Dallas, Texas. 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